Hyperpigmentation post laser hair removal in patients taking Vitamin D supplements

Saad Altalhab; Mohammed I AlJasser; Ziad M Alshaalan; Rima M Ahmad; Leena Alghamdi; Abdulaziz A Alnoshan

doi:10.4103/jdds.jdds_60_19

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ORIGINAL ARTICLE

Year : 2021 \| Volume : 25 \| Issue : 1 \| Page : 33-36

Hyperpigmentation post laser hair removal in patients taking Vitamin D supplements Saad Altalhab¹, Mohammed I AlJasser², Ziad M Alshaalan³, Rima M Ahmad⁴, Leena Alghamdi⁵, Abdulaziz A Alnoshan⁶ ¹ Department of Dermatology, College of Medicine, Al Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia ² Division of Dermatology, King Saud bin Abdulaziz University for Health Sciences; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia ³ Department of Medicine, Al Jouf University, Al Jouf, Saudi Arabia ⁴ Department of Medicine, American University of Beirut, Lebanon ⁵ Department of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia ⁶ Department of Medicine, Security Forces Hospital, Riyadh, Saudi Arabia Correspondence Address: Dr. Saad Altalhab Department of Dermatology, College of Medicine, Al Imam Mohammad Ibn Saud Islamic University, Riyadh Saudi Arabia Source of Support: None, Conflict of Interest: None DOI: 10.4103/jdds.jdds_60_19

Background: Laser hair removal (LHR) is a common procedure for the removal of unwanted hair. Although it is generally safe, it is associated with some adverse effects including hyperpigmentation. Purpose: In this study, we aimed to assess the prevalence of postlaser hyperpigmentation in patients taking Vitamin D supplements. Methods: This is a cross-sectional study of patients who underwent LHR. Each patient was interviewed and asked about their intake of Vitamin D supplements, and the primary outcome was whether hyperpigmentation was reported after LHR in the past 6 months. LHR treatment details were also documented. Results: A total of 508 patients were included with a mean age of 29 ± 9 years. Post-LHR hyperpigmentation was more prevalent in females and in those taking oral Vitamin D. Multivariate logistic regression analysis showed that Vitamin D intake was independently associated with more risk of hyperpigmentation post LHR (odds ratio [95% confidence interval]; 2.6 [1.17–5.80], P = 0.020). Conclusion: Vitamin D intake may be associated with an increased risk of hyperpigmentation post LHR. Causality cannot be assessed.



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