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Year : 2021  |  Volume : 25  |  Issue : 1  |  Page : 6-13

Clinico-epidemiological factors related to lichen planus and its clinical variants at a tertiary care hospital: A descriptive study

Department of Skin and VD, Topiwala National Medical College and B.Y.L. Nair Ch. Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Ankit Gupta
OPD No. 2-37, 2nd Floor, OPD Building, Nair Hospital, Mumbai Central, Mumbai - 400 008, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jdds.jdds_66_19

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Background: Lichen planus (LP) is an immune_mediated, chronic inflammatory disease involving skin, oral and genital mucosa, nails, and hair with several morphologic variants. The exact etiology remains unclear, but several factors have been implicated. Purpose: To study the clinico-epidemiological profile of patients of LP and its clinical variants and to find out whether LP is relatively uncommon in children. Methods: This prospective, cross-sectional, descriptive, time-bound, clinico-epidemiological study was conducted in the outpatient department of dermatology at a tertiary care hospital during the period of June 2017 to October 2018. A total of 170 patients were included in the study. Microsoft Excel and SPSS 23 software packages were used for data entry and statistical analysis. The results were averaged for each parameter for continuous data and numbers and percentage for categorical data. Statistical tests were applied wherever necessary. Results: The overall prevalence of LP was 0.4% (n = 170) out of 42,127 patients who attended the OPD during the study period. The gender-wise prevalence of LP was 41% among females and 59% among males, and the difference was not statistically significant (P = 0.3). The male-to-female ratio was 1.5:1. The highest prevalence among the variants of LP was of classical form (29%) and lowest was of inverse LP (0.6%). Overall, the mean age of the patients was 36 years, with a standard deviation of 17. There was one instance of LP occurring in both father and son. Conclusion: The most common age group of LP was 18 -40 years. Most patients came to seek health care within 1 year of beginning of disease. More than one variant of LP can coexist in the same individual. Childhood LP is not uncommon in the Indian subcontinent.

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