ORIGINAL ARTICLE
Year : 2022 | Volume
: 26 | Issue : 2 | Page : 73--76
Autologous platelet-rich fibrin membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers: A prospective study
Amina Asfiya1, Sacchidanand Sarvajnamurthy2, Fardeen Shariff3, Leelavathy Budamakuntala4
1 Department of Dermatology, Yenepoya Medical College, Deralakatte, Mangalore, Karnataka, India
2 Senior Consultant Dermatologist, Sujala Polyclinic and Lab, Bengaluru, Karnataka, India
3 Department of Orthopaedics, Yenepoya Medical College, Deralakatte, Mangalore, Karnataka, India
4 Department of Dermatology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India
Correspondence Address:
Dr. Amina Asfiya
Department of Dermatology, Venereology and Leprosy, Yenepoya Medical College, Deralakatte, Mangalore - 575 016, Karnataka
India
Background: Chronic nonhealing ulcers of the lower extremity are a cause of morbidity and mortality. The various treatment options available are limited and unsatisfactory. Promoting wound healing with an autologous platelet membrane could be a safe, easy, and inexpensive modality. Purpose: To assess an autologous platelet-rich fibrin (PRF) membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers. Methods: A prospective study enrolled 30 patients with chronic nonhealing leg ulcers. Autologous PRF was applied weekly for 6 weeks. At each visit, the ulcer healing was assessed with wound measurements and photographs. The treatment outcome was defined as a percentage in a change of area and volume of the ulcer at the end of the study period. Results: Thirty patients with chronic nonhealing leg ulcers were treated for 6 weeks. 100% improvement in area of the ulcer was seen in 43% ulcers. The mean percentage of improvement in area of the ulcer was 72%. The mean percentage of improvement in volume of the ulcer was 77%. The mean duration of healing was 5 weeks. Conclusion: This study was limited by the lack of a control group. Autologous PRF may be useful for the treatment of chronic nonhealing leg ulcers which can be done on an outpatient basis with minimum adverse effects.
How to cite this article:
Asfiya A, Sarvajnamurthy S, Shariff F, Budamakuntala L. Autologous platelet-rich fibrin membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers: A prospective study.J Dermatol Dermatol Surg 2022;26:73-76
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How to cite this URL:
Asfiya A, Sarvajnamurthy S, Shariff F, Budamakuntala L. Autologous platelet-rich fibrin membrane as a wound dressing in the treatment of chronic nonhealing leg ulcers: A prospective study. J Dermatol Dermatol Surg [serial online] 2022 [cited 2023 Mar 29 ];26:73-76
Available from: https://www.jddsjournal.org/article.asp?issn=2352-2410;year=2022;volume=26;issue=2;spage=73;epage=76;aulast=Asfiya;type=0 |
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